Expected outcomes
What should improve.
- Reduced regain velocity after dose taper
- More stable appetite and meal regularity
- Sustained body composition and energy trends
SIGNAL // LOADING
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Protocol Provider review
Post-GLP-1 maintenance stack
Weight-regain prevention after active medication-driven loss.
- Duration
- 12-36 weeks
- Phases
- 3
- Updated
- 2026-04-27
Medically reviewed byDr. Marcus Hale, DO
Metabolic + Men's Health Lead - updated April 2026How we review
Best fit
Who this protocol is built for.
We screen eligibility before any prescription enters the conversation. Decline is treated as an outcome, not a failure.
- Members tapering or stopping GLP-1 after target loss
- People with previous regain after medication discontinuation
- Patients transitioning to coaching-first maintenance
Contraindications
Who should avoid this path.
These are hard stops. We route into a different protocol or refer out, rather than working around a contraindication.
- Members still in unstable active titration phase
- Uncontrolled binge-eating patterns without behavioral support
- Untreated endocrine drivers of rapid regain
Execution
Phased protocol timeline.
Each phase has explicit entry criteria, actions, and exit conditions. The plan moves on data and tolerance, not a calendar.
Phase 01
Weeks 0-2
Exit planning
Set taper timeline, maintenance calories, and behavioral guardrails before dose changes.
- Define taper or hold strategy with provider review
- Set protein and resistance-training maintenance floor
- Establish weekly weight and appetite monitoring cadence
Phase 02
Weeks 3-10
Transition window
Manage appetite rebound and behavior friction during dose reduction.
- Use satiety-first meal structure and fiber escalation
- Increase coaching contact frequency during high-risk weeks
- Adjust plan immediately when regain trend exceeds threshold
Phase 03
Weeks 11-24+
Steady maintenance
Convert temporary guardrails into a repeatable baseline routine.
- Retest metabolic markers and adjust long-run plan
- Lock training progression and sleep schedule
- Define criteria for re-entry to medication if clinically justified
Stack components
What this protocol layers.
Prescription
Labs
Supplements
Coaching
- High Frequency Transition Coaching
- Satiety Protocol Reinforcement
- Weekly Trend Review
Risk picture
What we monitor closely.
- Appetite rebound and adherence drop during taper window
- Under-eating then rebound overeating cycles
- Psychological dependence on medication without behavior layer
Monitoring cadence
How we track progress.
- Weekly trend checks for weight, hunger, and adherence
- A1c, fasting insulin, lipid markers 8-12 weeks post-taper
- Trigger-based escalation plan when regain threshold is crossed
Labs and availability
Run this protocol where service is live.
Common questions
Post-GLP-1 maintenance stack
protocol questions, answered.
Evidence
What post-glp-1 maintenance stack
is built on.
Trials, regulatory guidance, and peer-reviewed evidence the protocol is anchored against.
Keep reading
Guides and pathways tied to this protocol
- Branded (Wegovy / Zepbound / Ozempic / Mounjaro) vs Compounded (503A / 503B pharmacy)
Compounded vs branded GLP-1: sourcing, cost, and what to trust
Branded GLP-1s are FDA-approved and FDA-reviewed for efficacy. Compounded versions use the same pharmaceutical-grade peptide from a licensed compounding...
Read - Guide
Holding the loss after GLP-1: protein, training, and the maintenance plan
The 60-80% regain statistic at 12-24 months after stopping GLP-1 isn't a medication failure - it's a foundation failure. Members who built protein, strength,...
Read - ALUKARD vs Function Health
ALUKARD vs Function Health: treatment execution versus lab breadth
Function Health is built around broad laboratory visibility. ALUKARD is built around turning biomarker signal into protocol execution. This comparison...
Read - Care pathway
Coaching
Protein, sleep, training, adherence. The plumbing most routines skip, wired to your labs and your real schedule.
Read - Guide
GLP-1 eligibility explained: who qualifies, who doesn't, and why
Most telehealth sites approve nearly every intake that clicks through. We don't. About one in five GLP-1 intakes gets routed elsewhere - thyroid history,...
Read - Care pathway
Weight Management
Most weight struggles have a metabolic driver the scale never shows. We find it, treat it, and only talk medication when the data says to.
Read
Build your plan
Run this protocol where the data points.
Take the assessment and we’ll route you into labs, a foundational stack, coaching, or provider review based on what you answer.